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The probe was passed over the cervical third to test for the presence of plaque.A disclosing agent may have been used to assist evaluation (Dento-Palque® Inava, Pierre Fabre Oral Care, France). A zero indicated no plaque present on the tooth; 1 indicated a film of plaque observable only after application of disclosing solution or by using the probe on the tooth surface; 2 represented moderate accumulation of soft deposits in the gingival pocket or on the tooth that could be seen by the naked eye; 3 represented an abundance of soft matter within the pocket or on the tooth.Major periodontal risk factors were recorded (age, gender, diabetes and smoking status), as well as plasma levels of inflammatory markers (CRP, orosomucoid, IL-6) and adipokines (adiponectin, leptin). A cross-sectional study was conducted to evaluate the relationship between periodontitis and the common systemic inflammatory markers in 32 morbidly obese patients recruited in a Clinical Nutrition department.All patients included in the sample exhibited evidence of periodontitis, 16 of whom were diagnosed as having severe disease. Periodontal condition was evaluated using pocket depth (PD) measurement, a classical clinical marker of ongoing periodontitis.

We hypothesized that periodontitis in morbidly obese subjects could alter the profile of inflammatory mediators.Before surgery, these patients underwent a periodontal screening at the Department of Odontology, Bretonneau Hospital (Paris, France).All patients, referred between September 2007 and July 2008, were considered for inclusion.Subjects did not demonstrate evidence of acute or chronic inflammatory disease, infectious diseases, viral infection, cancer and/or known alcohol consumption (20 g per day).Patients having rheumatoid arthritis, malignant disease, or a past history of cardiovascular disease were excluded from the study.

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Consequently, we conducted a study to determine the extent to which periodontitis influences systemic levels of inflammatory mediators in a group of morbidly obese patients.